Monday, 16 December 2019



•1999 Pharmacy Degree, University of Valencia

•2005 PhD in Inmunology, Autonomous University of Barcelona



•2016-       Independent Ramón y Cajal Research Group Leader

               Institute of Biomedicine of Valencia (Valencia, Spain) 

•2014-2016 Independent Research Group Leader Heinrich

               Heine University (Düsseldorf, Germany)

•2009-2014 Project group leader,

               Max Planck Institute for Molecular Biomedicine (Münster, Alemania)

•2005-2009 Post-doctoral Researcher

               Max Planck Institute for Molecular Biomedicine (Münster, Germany)

•2001-2005 Pre-doctoral Student

               Fundació irsiCaixa (Badalona, Spain)

•2004        Short-term visit

               Johns Hopkins Stem Cell Institute (Baltimore, USA)


• 2016  Beca Leonardo a Investigadores y Creadores Culturales (Fundación BBVA)

• 2013  NRW-Stem Cell Junior Research Group Award 


Selected publications (* co-first or co-corresponding author)


 1- Tapia N* and Schöler H.R*. Molecular obstacles to clinical translation of iPSCs. Cell Stem Cell. 2016 Sep 1;19(3):298-309


2- Tiemann U, Wu G, Marthaler AG, Schöler HR, Tapia N. Epigenetic memory is not intrinsic to transcription factor-mediated reprogramming. Stem Cell Reports. 2016 Jan 12;6(1):35-43


3- Kim SM, Flaßkamp H, Hermann A, Arauzo-Bravo MJ, Lee SC, Lee SH, Seo EH, Lee SH, Storch A, Lee HT, Schöler HR, Tapia N*, Han DW*. Direct conversion of mouse fibroblasts into induced neural stem cells. Nat Protocols. 2014 Apr;9(4):871-81


4- Tiemann U, Wu G, Marthaler AG, Adachi K, Wu G, Fischedick GUL, Arauzo-Bravo MJ, Schöler HR, Tapia N. Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Stem Cell Reports. 2014 Feb 20;2(3):351-65


5- Tapia N, Reinhardt P, Duemmler A, Wu G, Araúzo-Bravo MJ, Esch D, Greber B, Cojacaru V, Rascon CA, Tazaki A, Tanaka EM, Schöler HR. Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nat Communications. 2012;3:1279


6- Han DW*, Tapia N*, Hermann A, Hemmer K, Höing S, Araúzo-Bravo MJ, Zaehres H, Wu G, Frank S, Moritz S, Greber B, Yang JH, Lee HT, Schwamborn JC, Storch A, Schöler HR. Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell. 2012 Apr 6;10(4):465-72.